Click chemistry has the characteristics of mild conditions, good selectivity, high efficiency, fast kinetic reaction, high chemical selectivity, simple operation and free from the influence of water oxygen, etc., which can realize biocompatible small molecules for biological coupling with other substances. Thus, the target molecules (substrates, small molecule drugs) and specific biological molecules (such as proteins) are linked.

The concept of "Click chemistry" has made a great contribution to the field of chemical synthesis. It has become one of the most useful and attractive synthesis concepts in many fields such as drug development and biomedical materials.